Briana McDonald

Follow along with 49ers.com for in-game updates, highlights, stats and analysis during the team's Week 3 matchup at Empower Field at Mile High.

Game InformationSan Francisco 49ers vs. Denver BroncosSunday, September 25, 2022Empower Field at Mile HighAbout the MatchupTotal Matchups: 15Series Record: 49ers lead the series 8-749ers Away Record vs. Broncos: Broncos lead the series 4-2San Francisco 49ers

Head coach: Kyle Shanahan

Players to watch:

Offense

FB Kyle JuszczykOL Aaron BanksRB Jeff Wilson Jr.WR Brandon Aiyuk

Defense

LB Dre GreenlawCB Charvarius WardS Talanoa HufangaDL Nick BosaDenver Broncos

Head Coach: Nathaniel Hackett

Players to watch:

Offense

QB Russell WilsonWR Courtland SuttonRB Javonte WilliamsRB Melvin Gordon III

Defense

OLB Bradley ChubbS Justin SimmonsS Caden SternsDT D.J. JonesWeek 2 Images Up Next Latest Videos Channel Garoppolo, Warner, Kittle, Bosa: 'We've Still Got a lot of Football Left' Latest Videos Channel Kyle Shanahan Talks Injuries to Key Players Following 'SNF' Loss Latest Videos Channel 49ers Top Plays vs. the Broncos on 'Sunday Night Football' Latest Videos Channel Robbie Gould Puts Three on the Board with a 51-Yard Field Goal Latest Videos Channel Garoppolo Exploits Samuel's Mismatch for a 32-Yard Sideline Connection Latest Videos Channel ¡Sack del Novato Drake Jackson! Latest Videos Channel Kerry Hyder Jr. Takes Down Russell Wilson on 'Sunday Night Football' Latest Videos Channel Jimmy Garoppolo Connects with Brandon Aiyuk for a Touchdown Latest Videos Channel 'El Jefe' Jeff Wilson Jr. Mueve las Cadenas con una Corrida de 37 Yardas Latest Videos Channel Brandon Aiyuk Abre el Marcador Después de un Pase de Garoppolo Latest Videos Channel Jeff Wilson Jr.'s 37-Yard Run Moves the 49ers into the Red Zone Latest Videos Channel En Vivo Desde Denver para el Arranque de los 49ers Contra Broncos Latest Videos Channel Kittle, Bosa Talk 'Good Energy' Leading up to Primetime Matchup vs. Broncos Latest Videos Channel Kyle Shanahan on George Kittle: 'He's Good to Go' Latest Videos Channel Kittle: 'Feels Great to be Back on the Football Field' Latest Videos Channel Jimmy Garoppolo Talks Stepping Back Into QB1 Role Latest Videos Channel Ryans, Foerster on Young Players Being 'Put to the Test' Latest Videos Channel Dwelley, Woerner Discuss NFL Journeys, Dating Etiquette and More Fan Q's Latest Videos Channel 3 Puntos Claves: San Francisco 49ers vs. Denver Broncos Latest Videos Channel Yahoo! Sports Fantasy Football Rundown: 49ers vs. Broncos Latest Videos Channel San Francisco 49ers vs. Denver Broncos Week 3 Preview Latest Videos Channel Kyle Shanahan Outlines How New Players will Contribute to 49ers Offense Latest Videos Channel Al-Shaair, Purdy, McGlinchey, Juszczyk: Team is 'Excited' to Play in 'SNF' Latest Videos Channel Los 49ers: Inicia el Mes de la Herencia Latina con Alfredo Gutierrez  Latest Videos Channel 49 Hours: Battling for the Brotherhood Latest Videos Channel Mic'd Up: Fred Warner is 'Relentless' in 49ers Week 2 Win vs. Seahawks Latest Videos Channel Tacos de Asada, Birria, ¿Puedes Adivinar el Platillo Latino Favorito de los 49ers? Latest Videos Channel Jugadas Doradas: Lo Más Notable de Samuel, Hufanga y Otros Ante los Seahawks Latest Videos Channel Baldy's Breakdowns: How the 49ers Moved the Chains in Week 2 Latest Videos Channel The 49ers and the Honor Group Host the 2022 NorCal Honor Bowl Latest Videos Channel Garoppolo, Juszczyk, Warner, Samuel, Bosa Talk Players Stepping Up Latest Videos Channel 49ers Locker Room Praying for Trey Lance Following Week 2 Injury Latest Videos Channel 49ers Top Plays from Week 2 Win vs. Seahawks Latest Videos Channel Shanahan Evaluates 49ers Week 2 Victory vs. Seahawks Latest Videos Channel Banks, Armstead, Jennings, McGlinchey, Aiyuk: 'We Got Each Other's Back' Latest Videos Channel Jimmy Garoppolo Puts Up 6 on a Quarterback Sneak Latest Videos Channel Nick Bosa Engulfs Geno Smith for a Sack on First Play of the Second Half Latest Videos Channel Kyle Juszczyk Corre Sobre la Línea Defensiva Para un TD Latest Videos Channel Charvarius Ward Thwarts Seahawks Trick Play with Goal-Line INT Latest Videos Channel Kyle Juszczyk Plows into the End Zone for a Touchdown